Sepsis-induced cardiac disfunction (SICD) remains a poorly understood syndrome in sepsis in children. The criteria of septic shock adopted by the international consensus of the Society of Critical Care Medicine on January 21, 2024, based on the use of the Phoenix Sepsis scale, were used as the "gold standard". 22 children aged from 1 month to 17 years with suspected sepsis were examined. 2 groups of patients were formed, 1 group with SICD — 5 patients and the second group without SICD — 17 patients. As a result of a comprehensive study, it was revealed that the diagnostic criteria can be clinical and one laboratory criterion. Clinical criteria include: resistant sinus tachycardia 180-200 beats per minute or resistant bradycardia (relative risk (RR) 27, 95% confidence interval (CI) 1.68 — 431, z - 2.331, p=0.019, the number needed to treat (Harm) (NNT(Harm)) 1.385, 95% CI (Harm) 2.071 – 1.04). The laboratory criterion is the level of NT-PROBNP in the blood of 2094 pg/ml (sensitivity — 100%, specificity — 100%, area under curve ROC (AUCROC) — 1.0). The statistical power turned out to be higher than 0.8. The study indicates that the identified diagnostic criteria are sufficiently accurate for the diagnosis of this syndrome.

Keywords: sepsis, children, sepsis-induced cardiac disfunction, NT-PROBNP.

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